Combined Species Identification, Genotyping, and Drug Resistance Detection of Mycobacterium tuberculosis Cultures by MLPA on a Bead-Based Array
نویسندگان
چکیده
منابع مشابه
Combined Species Identification, Genotyping, and Drug Resistance Detection of Mycobacterium tuberculosis Cultures by MLPA on a Bead-Based Array
The population structure of Mycobacterium tuberculosis is typically clonal therefore genotypic lineages can be unequivocally identified by characteristic markers such as mutations or genomic deletions. In addition, drug resistance is mainly mediated by mutations. These issues make multiplexed detection of selected mutations potentially a very powerful tool to characterise Mycobacterium tubercul...
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tuberculosis remains a major public health problem in both developing and developed countries. drug-resistant tuberculosis is an increasing health problem and serious challenge to tuberculosis (tb) control programs. information about the susceptibility pattern of mycobacterium tuberculosis isolates against anti-tuberculosis drugs is an important aspect to tb control. the objectives of the study...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0043240